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羟脯氨酸生产厂家富阳东辰生物工程是一家羟脯氨酸生产企业,主营羟基脯氨酸,提供羟脯氨酸与脯氨酸价格、报价业务!

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  • 羟基脯氨酸的生产工艺
  • 本站编辑:浙江省富阳东辰生物工程有限公司发布日期:2019-05-08 18:54 浏览次数:

氨基酸的主要生产方法有发酵法、酶法、蛋白质水解提取法和化学合成法。目前多采用发酵方式。然而,由于羟脯氨酸的特殊结构,不能产生发酵法,而且化学合成法的成本过高,因此从胶原蛋白中分离和提取是一种重要的方法。蛋白质被酸、碱或蛋白质溶解酶水解,然后各种氨基酸分离纯化,简称水解法。主要有酸水解、碱水解和酶水解三种水解方法。碱方法可引起氨基酸的外消旋。酶法的缺点是不完全水解。它们很少用于氨基酸的生产。因此,酸水解一般用于制备羟脯氨酸。

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The main production methods of amino acids are fermentation, enzymatic method, protein hydrolysis extraction method and chemical synthesis method. At present, fermentation method is mostly used. However, because of the special structure of hydroxyproline, fermentation method can not be produced, and the cost of chemical synthesis method is too high, so isolation and extraction from collagen is an important way. Protein is hydrolyzed by acid, alkali or proteolytic enzymes, and then various amino acids are separated and purified, which is called hydrolysis method for short. There are three main hydrolysis methods: acid hydrolysis, alkali hydrolysis and enzymatic hydrolysis. Alkali method can cause racemization of amino acids. The disadvantage of enzymatic method is incomplete hydrolysis. Intermediate products such as peptides are abundant, the general time is long, and the bacteria are easily polluted. They are seldom used in the production of amino acids. Therefore, acid hydrolysis is generally used to prepare hydroxyproline.

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