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  • 脯氨酸在医药行业的应用
  • 本站编辑:浙江省富阳东辰生物工程有限公司发布日期:2019-08-22 06:43 浏览次数:

脯氨酸(Proline,缩写为Pro 或P),α-亚氨基酸,中性,等电点为6.30,水中溶解度比任何氨基酸都大,25℃时100g水中可溶162 g左右。易潮解不易得结晶,有甜味。与茚三酮溶液共热,生成黄色化合物。一旦进入肽链后,可发生羟基化作用,从而形成4-羟脯氨酸,是组成动物胶原蛋白的重要成分。羟脯氨酸也存在于多种植物蛋白质中,尤其与细胞壁的形成有关。植物体在干旱、高温、低温、盐渍等多种逆境下,常常有脯氨酸的明显积累。在临床、生物材料、工业等方面均有广泛应用



Proline(abbreviated as Pro or P), α-subamino acid, neutral, isoelectric point 6.30, solubility in water is greater than any amino acid, and about 162g of water is soluble at 25 °C. Easy to deliquescent is not easy to crystallize, sweet. It is co-heated with the ninhydrin solution to produce a yellow compound. Once in the peptide chain, hydroxylation can occur, forming 4-hydroxyproline, which is an important component of animal collagen. Hydroxyproline is also present in a variety of plant proteins, especially related to the formation of cell walls. Plant bodies often have obvious accumulation of proline under various adversity such as drought, high temperature, low temperature, and salt. It is widely used in clinical, biological materials, industry, etc..
Application in the pharmaceutical industry
Amino acid drugs. One of the raw materials of compound amino acid infusion. Used for malnutrition, protein deficiency, severe gastrointestinal diseases, Burns, and protein supplementation after surgery. No obvious side effects.

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